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Article

Nrf2 deficiency leads to behavioral, neurochemical and transcriptional changes in mice.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Oct 2013

Muramatsu Hiroyuki, Katsuoka Fumiki, Toide Katsuo, Shimizu Yusuke, Furusako Shoji, Yamamoto Masayuki

Abstract excerpt

Nrf2 is a transcription factor that regulates the antioxidant and detoxification enzyme genes and provides defense against oxidative and electrophilic stresses in various tissues. In brain, while neuroprotective functions of Nrf2 have been well documented, Nrf2 contribution to the brain function remains to be elucidated. To address this issue, we investigated whether Nrf2 deficiency affects psychological...

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Identifiers

PMID: 23890231
DOI: 10.1111/gtc.12083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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