Article
Combining HLA-DR risk alleles and anti-Epstein-Barr virus antibody profiles to stratify multiple sclerosis risk.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Mar 2014
Strautins K, Tschochner M, James I, Choo L, Dunn D S, Pedrini M, Kermode A, Carroll W, Nolan D
Abstract excerpt
BACKGROUND: Risk factors for multiple sclerosis (MS) include human leukocyte antigen (HLA)-DR and Epstein-Barr virus (EBV)-specific antibody responses, including an epitope within EBV nuclear antigen 1 (EBNA-1) that is of recent interest. OBJECTIVE: The objective of this paper is to assess case-control associations between MS risk and anti-EBV antibody levels as well as HLA-DR profiles, gender and age in a...
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