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Article

Osteopontin genetic variants are associated with overall survival in advanced non-small-cell lung cancer patients and bone metastasis.

Journal of experimental & clinical cancer research : CR - 24 Jul 2013

Chen Yunzhen, Liu Haichun, Wu Wenliang, Li Yi, Li Jianmin

Abstract excerpt

PURPOSE: Osteopontin (OPN) plays important roles in the modulation of apoptosis, angiogenesis, immune response, and tumor invasion. Elevated osteopontin expression has been reported in the lung cancer tissues compared to counterpart normal tissues. This study examined whether genetic variations in the osteopontin gene are associated with survival of lung cancer patients and occurrence rate of bone metastasis....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23883434
DOI: 10.1186/1756-9966-32-45
PMCID: PMC3728114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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