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Article

Osteopontin promoter polymorphisms at locus -443 are associated with metastasis and poor prognosis of human intrahepatic cholangiocarcinoma in Chinese population.

International journal of clinical and experimental pathology - 1 Jan 2014

Zhao Xiang-Qian, Ma Huan-Xian, Su Mao-Sheng, He Lei

Abstract excerpt

PURPOSE: Osteopontin (OPN) is known to be a secreted adhesive glycoprotein. Role of OPN in human intrahepatic cholangiocarcinoma (ICC) has not been well understood. This study explored whether genetic variations in the osteopontin gene are associated with ICC risk, progression and metastasis. MATERIAL AND METHODS: 260 patients with stages I to IV between 2008 and 2013 were recruited in this study and same number...

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Identifiers

PMID: 25400775
PMCID: PMC4230109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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