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Article

No association between germline variation in catechol-O-methyltransferase and colorectal cancer survival in postmenopausal women.

Menopause (New York, N.Y.) - 1 Apr 2014

Passarelli Michael N, Newcomb Polly A, Makar Karen W, Burnett-Hartman Andrea N, Phipps Amanda I, David Sean P, Hsu Li, Harrison Tabitha A, Hutter Carolyn M, Duggan David J, White Emily, Chan Andrew T, Peters Ulrike

Abstract excerpt

OBJECTIVE: Sex steroid hormones play a role in colorectal cancer (CRC) development, but little is known about their influence on tumor progression and metastasis. Because catechol-O-methyltransferase (COMT; 22q11.21) activity is an important component of estrogen-mediated carcinogenesis, we hypothesized that germline variation in COMT may be associated with CRC survival. METHODS: We identified 10 single...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23880798
DOI: 10.1097/GME.0b013e31829e498d
PMCID: PMC3865220

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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No association between germline variation in catechol-O-methyltransferase and colorectal cancer survival in postmenopausal women.PMID 23880798Read ↗

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