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Article

Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein.

Proceedings of the National Academy of Sciences of the United States of America - 6 Aug 2013

Zalckvar Einat, Paulus Christina, Tillo Desiree, Asbach-Nitzsche Alexandra, Lubling Yaniv, Winterling Carla, Strieder Nicholas, Mücke Katrin, Goodrum Felicia, Segal Eran, Nevels Michael

Abstract excerpt

Human CMV (hCMV) establishes lifelong infections in most of us, causing developmental defects in human embryos and life-threatening disease in immunocompromised individuals. During productive infection, the viral >230,000-bp dsDNA genome is expressed widely and in a temporal cascade. The hCMV genome does not carry histones when encapsidated but has been proposed to form nucleosomes after release into the host...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23878222
DOI: 10.1073/pnas.1305548110
PMCID: PMC3740854

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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