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Article

How to control an infectious bead string: nucleosome‐based regulation and targeting of herpesvirus chromatin

27 Apr 2011

Abstract excerpt

Herpesvirus infections of humans can cause a broad variety of symptoms ranging from mild afflictions to life-threatening disease. During infection, the large double-stranded DNA genomes of all herpesviruses are transcribed, replicated and encapsidated in the host cell nucleus, where DNA is typically structured and manoeuvred through nucleosomes. Nucleosomes individually assemble DNA around core histone octamers...

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PMID: 21538665
DOI: 10.1002/rmv.690

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