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Article

Detection of new point mutations of BRCA1 and BRCA2 in breast cancer patients.

Biochemical genetics - 1 Feb 2014

Bensam Moufida, Hafez Elsayed, Awad Doaa, El-Saadani Muhammad, Balbaa Mahmoud

Abstract excerpt

This study included 20 selected female patients with breast cancer, 30 of their female relatives (sisters and daughters), and 10 healthy females as a control group. Genomic DNA was extracted from peripheral blood lymphocytes of all the subjects, and the polymerase chain reaction was carried out using specific primers for BRCA1 (exons 2 and 8) and BRCA2 (exons 9, 11, and 21). The mutations were detected using a...

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Source

Identifiers

PMID: 23877192
DOI: 10.1007/s10528-013-9623-8

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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