Article
Novel mutations in the BRCA1 and BRCA2 genes in Iranian women with early-onset breast cancer.
Breast cancer research : BCR - 1 Jan 2002
Yassaee Vahid R, Zeinali Sirous, Harirchi Iraj, Jarvandi Soghra, Mohagheghi Mohammad A, Hornby David P, Dalton Ann
Abstract excerpt
BACKGROUND: Breast cancer is the most common female malignancy and a major cause of death in middle-aged women. So far, germline mutations in the BRCA1 and BRCA2 genes in patients with early-onset breast and/or ovarian cancer have not been identified within the Iranian population. METHODS: With the collaboration of two main centres for cancer in Iran, we obtained clinical information, family history and...
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