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Article

Comprehensive mutational analysis of BRCA1/BRCA2 for Korean breast cancer patients: evidence of a founder mutation.

Clinical genetics - 1 Aug 2009

Seong M-W, Cho Si, Noh D-Y, Han W, Kim S-W, Park C-M, Park H-W, Kim S Y, Kim J Y, Park S S

Abstract excerpt

The BRCA1 and BRCA2 genes are the strongest susceptibility genes identified for breast cancer worldwide. However, BRCA1/BRCA2 have been incompletely investigated due to their large size and the genomic rearrangements that occasionally occur within them. Here we performed a comprehensive mutational analysis for BRCA1/BRCA2 in 206 Korean patients with breast cancer. We analyzed all exons and flanking regions of...

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Identifiers

PMID: 19656164
DOI: 10.1111/j.1399-0004.2009.01202.x

Genes

BRCA2
BRCA1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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