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Article

Imprinted chromatin around DIRAS3 regulates alternative splicing of GNG12-AS1, a long noncoding RNA.

American journal of human genetics - 8 Aug 2013

Niemczyk Malwina, Ito Yoko, Huddleston Joanna, Git Anna, Abu-Amero Sayeda, Caldas Carlos, Moore Gudrun E, Stojic Lovorka, Murrell Adele

Abstract excerpt

Imprinted gene clusters are regulated by long noncoding RNAs (lncRNAs), CCCTC binding factor (CTCF)-mediated boundaries, and DNA methylation. DIRAS3 (also known as ARH1 or NOEY1) is an imprinted gene encoding a protein belonging to the RAS superfamily of GTPases and is located within an intron of a lncRNA called GNG12-AS1. In this study, we investigated whether GNG12-AS1 is imprinted and coregulated with DIRAS3....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23871723
DOI: 10.1016/j.ajhg.2013.06.010
PMCID: PMC3738830

Genes

GNG12
DIRAS3
CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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