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Article

Characterization of novel paternal ncRNAs at the Plagl1 locus, including Hymai, predicted to interact with regulators of active chromatin.

PloS one - 1 Jan 2012

Iglesias-Platas Isabel, Martin-Trujillo Alex, Cirillo Davide, Court Franck, Guillaumet-Adkins Amy, Camprubi Cristina, Bourc'his Deborah, Hata Kenichiro, Feil Robert, Tartaglia Gian, Arnaud Philippe, Monk David

Abstract excerpt

Genomic imprinting is a complex epigenetic mechanism of transcriptional control that utilizes DNA methylation and histone modifications to bring about parent-of-origin specific monoallelic expression in mammals. Genes subject to imprinting are often organised in clusters associated with large non-coding RNAs (ncRNAs), some of which have cis-regulatory functions. Here we have undertaken a detailed allelic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22723905
DOI: 10.1371/journal.pone.0038907
PMCID: PMC3378578

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