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Article

The landscape of allelic expression and DNA methylation at the bovine SGCE/PEG10 locus.

Animal genetics - 1 Jun 2024

Zhang Yinjiao, Zhang Cui, Chen Weina, Huo Haonan, Li Shujing, Yu Wenli, Jin Lanjie, Wang Kun, Li Shijie

Abstract excerpt

Genomic imprinting is an epigenetic regulation in mammals in which a small subset of genes is monoallelically expressed dependent on their parental origin. A large imprinted domain, SGCE/PEG10 locus, is located on human chromosome 7q21s and mouse proximal chromosome 6. However, genomic imprinting of bovine SGCE/PEG10 cluster has not been systematically studied. In this study, we investigated allele expression of...

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PMID: 38594908
DOI: 10.1111/age.13429

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