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Article

Imprinting at the PLAGL1 domain is contained within a 70-kb CTCF/cohesin-mediated non-allelic chromatin loop.

Nucleic acids research - 1 Feb 2013

Iglesias-Platas Isabel, Court Franck, Camprubi Cristina, Sparago Angela, Guillaumet-Adkins Amy, Martin-Trujillo Alex, Riccio Andrea, Moore Gudrun E, Monk David

Abstract excerpt

Paternal duplications of chromosome 6q24, a region that contains the imprinted PLAGL1 and HYMAI transcripts, are associated with transient neonatal diabetes mellitus. A common feature of imprinted genes is that they tend to cluster together, presumably as a result of sharing common cis-acting regulatory elements. To determine the extent of this imprinted cluster in human and mouse, we have undertaken a systematic...

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Share to CCCTC-Binding Factor
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 6

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Share to Genes, Tumor Suppressor

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Source

Open in PubMed Open full text

Identifiers

PMID: 23295672
DOI: 10.1093/nar/gks1355
PMCID: PMC3575839

Genes

PLAGL1
CTCF
RAD21
SMC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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