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Article

Aberrant methylation of imprinted genes is associated with negative hormone receptor status in invasive breast cancer.

International journal of cancer - 1 Aug 2015

Barrow Timothy M, Barault Ludovic, Ellsworth Rachel E, Harris Holly R, Binder Alexandra M, Valente Allyson L, Shriver Craig D, Michels Karin B

Abstract excerpt

Epigenetic regulation of imprinted genes enables monoallelic expression according to parental origin, and its disruption is implicated in many cancers and developmental disorders. The expression of hormone receptors is significant in breast cancer because they are indicators of cancer cell growth rate and determine response to endocrine therapies. We investigated the frequency of aberrant events and variation in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25560175
DOI: 10.1002/ijc.29419
PMCID: PMC4437845

Genes

IGF2
DIRAS3
GRB10
MEST
PEG3
SNRPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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