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Article

Role of FDFT1 polymorphism for fibrosis progression in patients with chronic hepatitis C.

Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2014

Stättermayer Albert F, Rutter Karoline, Beinhardt Sandra, Wrba Fritz, Scherzer Thomas-Matthias, Strasser Michael, Hofer Harald, Steindl-Munda Petra, Trauner Michael, Ferenci Peter

Abstract excerpt

BACKGROUND: In chronic hepatitis C (CHC), steatosis is associated with fibrosis and impaired response to antiviral therapy. Recently, a polymorphism of single nucleotide polymorphism SNP rs2645424 of farnesyl diphosphate farnesyl transferase 1 (FDFT1) was identified in NAFLD/NASH as a possible causal link to steatosis and fibrosis progression. SNP rs738409 in the adiponutrin gene (PNPLA3) is a well described...

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Source

Identifiers

PMID: 23870067
DOI: 10.1111/liv.12269

Genes

FDFT1
PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Role of FDFT1 polymorphism for fibrosis progression in patients with chronic hepatitis C.PMID 23870067Read ↗

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