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Article

Tumor protein D52 controls trafficking of an apical endolysosomal secretory pathway in pancreatic acinar cells.

American journal of physiology. Gastrointestinal and liver physiology - 15 Sept 2013

Messenger Scott W, Thomas Diana D H, Falkowski Michelle A, Byrne Jennifer A, Gorelick Fred S, Groblewski Guy E

Abstract excerpt

Zymogen granule (ZG) formation in acinar cells involves zymogen cargo sorting from trans-Golgi into immature secretory granules (ISGs). ISG maturation progresses by removal of lysosomal membrane and select content proteins, which enter endosomal intermediates prior to their apical exocytosis. Constitutive and stimulated secretion through this mechanism is termed the constitutive-like and minor-regulated pathways,...

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Share to Acinar Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exocytosis

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Source

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Identifiers

PMID: 23868405
DOI: 10.1152/ajpgi.00143.2013
PMCID: PMC3761242

Genes

LAMP1
EEA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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