Article
A role for tumor protein TPD52 phosphorylation in endo-membrane trafficking during cytokinesis.
Biochemical and biophysical research communications - 26 Nov 2010
Thomas Diana D H, Frey Christina L, Messenger Scott W, August Benjamin K, Groblewski Guy E
Abstract excerpt
Tumor protein D52 is expressed at high levels in exocrine cells containing large secretory granules where it regulates Ca(2+)-dependent protein secretion; however, D52 expression is also highly induced in multiple cancers. The present study investigated a role for the Ca(2+)-dependent phosphorylation of D52 at the single major phospho-acceptor site serine 136 on cell division. Ectopic expression of wild type D52...
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