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Article

Design and application of a novel PNA probe for the detection at single cell level of JAK2V617F mutation in Myeloproliferative Neoplasms.

BMC cancer - 18 Jul 2013

Bracco Enrico, Rosso Valentina, Serra Anna, Carnuccio Francesca, Gaidano Valentina, Nicoli Paolo, Musto Pellegrino, Saglio Giuseppe, Frassoni Francesco, Cilloni Daniela

Abstract excerpt

BACKGROUND: Mutation(s) of the JAK2 gene (V617F) has been described in a significant proportion of Philadelphia negative Myeloproliferative Neoplasms (MPN) patients and its detection is now a cornerstone in the diagnostic algorithm. METHODS: We developed a novel assay based on peptide nucleic aci...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23865766
DOI: 10.1186/1471-2407-13-348
PMCID: PMC3728119

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23865766-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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