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Article

Relevance of JAK2V617F positivity to hematological diseases--survey of samples from a clinical genetics laboratory.

Journal of hematology & oncology - 14 Jan 2011

Zhao Wanming, Gao Rufei, Lee Jiyun, Xing Shu, Ho Wanting T, Fu Xueqi, Li Shibo, Zhao Zhizhuang J

Abstract excerpt

BACKGROUND: JAK2V617F is found in the majority of patients with Ph- myeloproliferative neoplasms (MPNs) and has become a valuable marker for diagnosis of MPNs. However, it has also been found in many other hematological diseases, and some studies even detected the presence of JAK2V617F in normal blood samples. This casts doubt on the primary role of JAK2V617F in the pathogenesis of MPNs and its diagnostic value....

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Identifiers

PMID: 21235771
DOI: 10.1186/1756-8722-4-4
PMCID: PMC3032761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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