Article
Detection of DNA induced gold nanoparticle aggregation with dark field imaging.
Chemical communications (Cambridge, England) - 4 Sept 2013
Bu Tong, Zako Tamotsu, Fujita Masahiro, Maeda Mizuo
Abstract excerpt
Dark field imaging was employed to visualize and quantify complementary DNA-induced gold nanoparticle aggregation at the single-particle level, with a detection limit of 100 fM DNA, which allows the highly sensitive detection of single nucleotide polymorphisms (SNPs). Results suggested that the aggregation process is consistent with the cluster-cluster model.
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