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Article

CK1δ kinase activity is modulated by Chk1-mediated phosphorylation.

PloS one - 1 Jan 2013

Bischof Joachim, Randoll Sven-Jannis, Süßner Nadine, Henne-Bruns Doris, Pinna Lorenzo A, Knippschild Uwe

Abstract excerpt

CK1δ, a member of the casein kinase 1 family, is involved in the regulation of various cellular processes and has been associated with the pathophysiology of neurodegenerative diseases and cancer. Therefore recently, interest in generating highly specific inhibitors for personalized therapy has increased enormously. However, the efficacy of newly developed inhibitors is affected by the phosphorylation state of...

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PMID: 23861943
DOI: 10.1371/journal.pone.0068803
PMCID: PMC3701638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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