Article
Alterations in the frequency of trinucleotide repeat dynamic mutations in offspring conceived through assisted reproductive technology.
Human reproduction (Oxford, England) - 1 Sept 2013
Zheng Ying-Ming, Li Li, Zhou Li-Ming, Le Fang, Cai Li-Yi, Yu Ping, Zhu Yu-Rong, Liu Xiao-Zhen, Wang Li-Ya, Li Le-Jun, Lou Yi-Yun, Xu Xiang-Rong, Lou Hang-Ying, Zhu Xiao-Ming, Sheng Jian-Zhong, Huang He-Feng, Jin Fan
Abstract excerpt
STUDY QUESTION: How does the frequency of trinucleotide repeat dynamic mutations in offspring conceived through assisted reproductive technology (ART) compare with the frequency of these mutations in control offspring conceived from spontaneous pregnancies? SUMMARY ANSWER: There is a slight increase in dynamic mutation instability in offspring conceived through ART compared with the naturally conceived offspring....
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