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Article

Screening and instability of FMR1 alleles in a prospective sample of 24,449 mother-newborn pairs from the general population.

Clinical genetics - 1 Dec 2009

Lévesque S, Dombrowski C, Morel M-L, Rehel R, Côté J-S, Bussières J, Morgan K, Rousseau F

Abstract excerpt

To study the instability of FMR1 triplet repeats in the general population, we screened a prospective sample of 24,449 anonymized mother-offspring pairs and analyzed transmissions of intermediate-size (45-54 triplets) and premutation-size (55-200 triplets) alleles. We screened all mothers for alleles > or = 45 triplets by Southern blot and studied transmission of 545 maternal alleles to their offspring using...

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Source

Identifiers

PMID: 19863547
DOI: 10.1111/j.1399-0004.2009.01237.x

Genes

FMR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Screening and instability of FMR1 alleles in a prospective sample of 24,449 mother-newborn pairs from the general population.PMID 19863547Read ↗

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