Article
Collagen type I alpha 1 gene polymorphism in premature ovarian failure.
Srpski arhiv za celokupno lekarstvo - 1 Jan 2000
Vujović Svetlana, Kanazir Selma, Ivović Miomira, Tancić-Gajić Milina, Perović Milka, Baltić Svetlana, Marina Ljiljana, Barać Marija, Ivanisević Maja, Micić Jelena, Micić Dragan
Abstract excerpt
INTRODUCTION: Premature ovarian failure (POF) is characterized by amenorrhea, hypergonadotropism and hypoestrogenism in women bellow 40 years. Osteoporosis is one of the late complications of POF. OBJECTIVE: To correlate collagen type I alpha1 (COLIA1) gene polymorphism with bone mineral density (BMD) in women with POF. METHODS: We determined the COLIA1 genotypes SS, Ss, ss in 66 women with POF. Single nucleotide...
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