Article
Polymorphisms of collagen 1A1 (COL1A1) gene and their relation to bone mineral density in postmenopausal women.
Ginekologia polska - 1 Dec 2015
Majchrzycki Marian, Bartkowiak-Wieczorek Joanna, Wolski Hubert, Drews Krzysztof, Bogacz Anna, Czerny Bogusław, Zagrodnik-Ułan Edyta, Seremak-Mrozikiewicz Agnieszka
Abstract excerpt
OBJECTIVES: The goal of this study was to evaluate the frequency of Sp1 +1245G>T (rs 1800012) and -199 7G>T (rs 1107946) COL1A1 gene polymorphisms in postmenopausal women with osteoporosis and osteopenia as well as assessing their relations with the clinical parameters and parameters of bone turnover. STUDY DESIGN: The study included 538 (236 postmenopausal and 302 healthy reproductive) Polish women. The...
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