Article
Does COLIA1 SP1-binding site polymorphism predispose women to pelvic organ prolapse?
International urogynecology journal and pelvic floor dysfunction - 1 Sept 2009
Feiner Benjamin, Fares Fuad, Azam Nail, Auslender Ron, David Miriam, Abramov Yoram
Abstract excerpt
INTRODUCTION AND HYPOTHESIS: COLIA1 polymorphism is associated with increased risk for stress urinary incontinence. We hypothesize that a similar association exists with pelvic organ prolapse (POP). METHODS: Patients with advanced prolapse and healthy controls were evaluated by interview, validated questionnaires, and pelvic examination. DNA was extracted from peripheral blood, and polymerase chain reaction was...
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