Article

Comparison of whole-exome, whole-transcriptome genomic profiling and targeted sequencing with 50-gene panels in advanced solid tumors

2026-08-12

Abstract excerpt

Abstract There are a growing number of options for therapies matched to molecular biomarkers in solid tumors. This study evaluated the value of genomic profiling in advanced solid tumors using whole-exome, whole-transcriptome sequencing (WES/WTS) in comparison to 50-gene panels. We retrospectively reviewed clinical reports from tumor samples tested with a WES/WTS assay to determine the proportion of samples across...

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Literature Corpus work: 75e0e339-8838-547c-b2d5-f128ff2c21af
DOI: 10.1038/s41598-026-64008-7

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