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Article

Polymorphisms in CYP2D6 may predict methamphetamine related heart failure.

Clinical toxicology (Philadelphia, Pa.) - 1 Aug 2013

Sutter M E, Gaedigk A, Albertson T E, Southard J, Owen K P, Mills L D, Diercks D B

Abstract excerpt

BACKGROUND: Methamphetamine (METH) has been associated with a dilated cardiomyopathy. The first and rate-limiting step of metabolism is dependent on the polymorphic enzyme CYP2D6. OBJECTIVES: To evaluate if polymorphisms in CYP2D6 can be associated with the development of a methamphetamine-induced cardiomyopathy. METHODS: We performed a prospective case-control pilot study. Cases were defined by a urinary drug...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23855716
DOI: 10.3109/15563650.2013.818684

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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