Article
Genetic analysis of the rhabdomyolysis-associated genes in forensic autopsy cases of methamphetamine abusers.
Legal medicine (Tokyo, Japan) - 1 Jan 2011
Matsusue Aya, Hara Kenji, Kashiwagi Masayuki, Kageura Mitsuyoshi, Sugimura Tomoko, Kubo Shin-ichi
Abstract excerpt
Methamphetamine (MA) use sometimes causes rhabdomyolysis, which has been associated with mortality. We analyzed potential rhabdomyolysis-susceptibility genes from autopsy samples of 18 methamphetamine abusers. We examined mutations in the ryanodine receptor 1 (RYR 1), carnitine palmitoyltransferase II (CPT II), very long-chain acyl-CoA dehydrogenase (VLCAD), and cytochrome P450 (CYP) 2D6 genes. Different RYR1...
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