Article
Response to methadone maintenance treatment is associated with the MYOCD and GRM6 genes.
Molecular diagnosis & therapy - 1 Jun 2010
Fonseca Francina, Gratacòs Mònica, Escaramís Geòrgia, De Cid Rafael, Martín-Santos Rocío, Fernández-Espejo Emilio, Estivill Xavier, Torrens Marta
Abstract excerpt
BACKGROUND: There is increasing interest in the pharmacogenetic basis for explaining differences between patients in treatment outcome among methadone-treated subjects. Most studies have focused on genetic polymorphisms related to methadone pharmacokinetics and, to a lesser extent, those genes implicated in the pharmacodynamics of methadone. OBJECTIVE: This study aimed to investigate the associations between...
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