Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PIK3CA mutations and PTEN loss in salivary duct carcinomas.

The American journal of surgical pathology - 1 Aug 2013

Griffith Christopher C, Seethala Raja R, Luvison Alyssa, Miller Megan, Chiosea Simion I

Abstract excerpt

Salivary duct carcinoma (SDC) is an aggressive malignancy that frequently presents at an advanced stage. Mutations/amplification of the gene encoding the p110α catalytic subunit of phosphoinositide 3-kinase (PIK3CA) and/or loss of the phosphatase and tensin homolog (PTEN) are known to activate th...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma
Share to Chromosomes, Human, Pair 10
Share to Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Hemizygote

Share to Monosomy

Share to PTEN Phosphohydrolase

Share to Salivary Gland Neoplasms

Source

Identifiers

PMID: 23851329
DOI: 10.1097/PAS.0b013e3182880d5a

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23851329-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PIK3CA mutations and PTEN loss in salivary duct carcinomas.PMID 23851329Read ↗

Oncogenic PIK3CA mutation and dysregulation in human salivary duct carcinoma.Semantic proximity Read ↗

Mutational analysis of PI3K/AKT and RAS/RAF pathway activation in malignant salivary gland tumours with a new mutation of PIK3CA.Semantic proximity Read ↗

High-throughput profiling identifies clinically actionable mutations in salivary duct carcinoma.Semantic proximity Read ↗

PIK3CA mutations in mucinous cystic neoplasms of the pancreas.Semantic proximity Read ↗

Analysis of PIK3CA and Akt/protein kinase B in head and neck squamous cell carcinoma.Semantic proximity Read ↗

<i>PIK3CA</i> mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinomaSemantic proximity Read ↗

PIK3CA, HRAS and PTEN in human papillomavirus positive oropharyngeal squamous cell carcinoma.Semantic proximity Read ↗

Loss of PTEN is associated with elevated EGFR and HER2 expression and worse prognosis in salivary gland cancerSemantic proximity Read ↗

Expression and mutation patterns of p53 in benign and malignant salivary gland tumors.Semantic proximity Read ↗

PIK3CA mutations in intraductal papillary mucinous neoplasm/carcinoma of the pancreas.Semantic proximity Read ↗

Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma.Semantic proximity Read ↗

Genomic gain of PIK3CA and increased expression of p110alpha are associated with progression of dysplasia into invasive squamous cell carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.