Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-throughput profiling identifies clinically actionable mutations in salivary duct carcinoma.

Journal of translational medicine - 25 Oct 2014

Ku Bo Mi, Jung Hyun Ae, Sun Jong-Mu, Ko Young Hyeh, Jeong Han-Sin, Son Young-Ik, Baek Chung-Hwan, Park Keunchil, Ahn Myung-Ju

Abstract excerpt

BACKGROUND: Salivary duct carcinoma (SDC) is a highly aggressive subtype of salivary gland cancers and there is no established standard therapy for this disease. Thus, development of molecular markers for SDC will be important to guide the diagnosis and therapy of this aggressive tumor. METHODS: We performed next-generation sequencing using the Ion Torrent AmpliSeq cancer panel, which explores the mutational...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to ERBB2 gene

Share to ERBB3 gene

Share to High-Throughput Nucleotide Sequencing

Share to Mutation

Share to Salivary Gland Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 25343854
DOI: 10.1186/s12967-014-0299-6
PMCID: PMC4216375

Genes

ERBB2
EGFR
ERBB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-throughput profiling identifies clinically actionable mutations in salivary duct carcinoma.PMID 25343854Read ↗

Detection of novel actionable genetic changes in salivary duct carcinoma helps direct patient treatment.Semantic proximity Read ↗

Integrative genomic analysis of salivary duct carcinoma.Semantic proximity Read ↗

Salivary duct carcinoma: An aggressive salivary gland malignancy with opportunities for targeted therapy.Semantic proximity Read ↗

Comprehensive Molecular Characterization of Salivary Duct Carcinoma Reveals Actionable Targets and Similarity to Apocrine Breast Cancer.Semantic proximity Read ↗

Oncogenic PIK3CA mutation and dysregulation in human salivary duct carcinoma.Semantic proximity Read ↗

Novel therapeutic targets in salivary duct carcinoma uncovered by comprehensive molecular profilingSemantic proximity Read ↗

Genetic mutations in salivary duct carcinoma.Semantic proximity Read ↗

Genomic landscape of salivary gland tumors.Semantic proximity Read ↗

Comprehensive genomic profiling of salivary mucoepidermoid carcinomas reveals frequent BAP1, PIK3CA, and other actionable genomic alterations.Semantic proximity Read ↗

Profiling of 149 Salivary Duct Carcinomas, Carcinoma Ex Pleomorphic Adenomas, and Adenocarcinomas, Not Otherwise Specified Reveals Actionable Genomic Alterations.Semantic proximity Read ↗

Detailed genome-wide SNP analysis of major salivary carcinomas localizes subtype-specific chromosome sites and oncogenes of potential clinical significance.Semantic proximity Read ↗

Targeted next generation sequencing of parotid gland cancer uncovers genetic heterogeneity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.