Article
Combined function of HoxA and HoxB clusters in neural crest cells.
Developmental biology - 1 Oct 2013
Vieux-Rochas Maxence, Mascrez Bénédicte, Krumlauf Robb, Duboule Denis
Abstract excerpt
The evolution of chordates was accompanied by critical anatomical innovations in craniofacial development, along with the emergence of neural crest cells. The potential of these cells to implement a craniofacial program in part depends upon the (non-)expression of Hox genes. For instance, the development of jaws requires the inhibition of Hox genes function in the first pharyngeal arch. In contrast, Hox gene...
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