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Article

A sphingosine 1-phosphate receptor 2 selective allosteric agonist.

Bioorganic & medicinal chemistry - 1 Sept 2013

Satsu Hideo, Schaeffer Marie-Therese, Guerrero Miguel, Saldana Adrian, Eberhart Christina, Hodder Peter, Cayanan Charmagne, Schürer Stephan, Bhhatarai Barun, Roberts Ed, Rosen Hugh, Brown Steven J

Abstract excerpt

Molecular probe tool compounds for the Sphingosine 1-phosphate receptor 2 (S1PR2) are important for investigating the multiple biological processes in which the S1PR2 receptor has been implicated. Amongst these are NF-κB-mediated tumor cell survival and fibroblast chemotaxis to fibronectin. Here we report our efforts to identify selective chemical probes for S1PR2 and their characterization. We employed high...

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Identifiers

PMID: 23849205
DOI: 10.1016/j.bmc.2013.06.012
PMCID: PMC3786410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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