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Article

RARα2 expression confers myeloma stem cell features

12 Jul 2013

Abstract excerpt

We previously demonstrated that RARα2 expression is increased in CD138 selected plasma cells of relapsed multiple myelomas (MMs), and increased expression was linked to poor prognosis in newly diagnosed MM patients. In the present study, we demonstrate that increased RARα2 confers myeloma stem cell features. Higher expression of RARα2 was identified in the multiple myeloma stem cell (MMSC) fraction....

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PMID: 23847194
DOI: 10.1182/blood-2013-02-482919

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