Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ABCG2 expression, function, and promoter methylation in human multiple myeloma

18 Aug 2006

Abstract excerpt

We investigated the role of the breast cancer resistance protein (BCRP/ABCG2) in drug resistance in multiple myeloma (MM). Human MM cell lines, and MM patient plasma cells isolated from bone marrow, were evaluated for ABCG2 mRNA expression by quantitative polymerase chain reaction (PCR) and ABCG2 protein, by Western blot analysis, immunofluorescence microscopy, and flow cytometry. ABCG2 function was determined by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Glycosylation and Glycoproteins Research
Share to Liver physiology and pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16917002
DOI: 10.1182/blood-2005-10-009084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ABCG2 expression, function, and promoter methylation in human multiple myelomaPMID 16917002Read ↗

Inherited variation in the xenobiotic transporter pathway and survival of multiple myeloma patients.Semantic proximity Read ↗

Development of Gene Expression–Based Score to Predict Sensitivity of Multiple Myeloma Cells to DNA Methylation InhibitorsSemantic proximity Read ↗

RARα2 expression confers myeloma stem cell featuresSemantic proximity Read ↗

Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expressionSemantic proximity Read ↗

Multidrug resistance gene expression and ABCB1 SNPs in plasma cell myeloma.Semantic proximity Read ↗

Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.Semantic proximity Read ↗

ABCG2: determining its relevance in clinical drug resistance.Semantic proximity Read ↗

Acquired resistance to bispecific antibodies by genetic or epigenetic inactivation of the target in multiple myelomaSemantic proximity Read ↗

DNA methyltransferase inhibitors upregulate CD38 protein expression and enhance daratumumab efficacy in multiple myelomaSemantic proximity Read ↗

Chemotherapeutic Drug-Induced ABCG2 Promoter Demethylation as a Novel Mechanism of Acquired Multidrug ResistanceSemantic proximity Read ↗

Integrated molecular profiling of SOD2 expression in multiple myelomaSemantic proximity Read ↗

Pyruvate kinase isoform M2 (PKM2) participates in multiple myeloma cell proliferation, adhesion and chemoresistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.