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Article

HIF1A (rs11549465) and AKNA (rs10817595) Gene Polymorphisms Are Associated with Primary Sjögren's Syndrome.

BioMed research international - 1 Jan 2017

Hernández-Molina Gabriela, Rodríguez-Pérez José Manuel, Fernández-Torres Javier, Lima Guadalupe, Pérez-Hernández Nonanzit, López-Reyes Alberto, Martínez-Nava Gabriela Angélica

Abstract excerpt

Objective. To evaluate the allele and genotype frequencies of polymorphic sites of HIF1A and ANKA genes in primary Sjögren's syndrome (pSS). Methods. We included 110 patients with pSS and 141 ethnically matched healthy controls. Three HIF1A gene polymorphisms (Pro582Ser, Ala588Thr, and C191T) and two AKNA gene polymorphisms (-1372C>A and Pro624Leu) were genotyped using TaqMan probes in a Real-Time PCR instrument....

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Identifiers

PMID: 28484714
DOI: 10.1155/2017/5845849
PMCID: PMC5397622

Genes

AKNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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