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Article

Primary Sjӧgren's syndrome: Clinical phenotypes, outcome and the development of biomarkers.

Autoimmunity reviews - 1 Jul 2016

Goules Andreas V, Tzioufas Athanasios G

Abstract excerpt

Primary Sjӧgren's syndrome (pSS) is a complex autoimmune disease with distinct clinical phenotypes and variable outcomes. The systemic form of the disease is characterized by immune complex mediated manifestations and is complicated by lymphoma as a result of a polyclonal B cell hyperactivity that is evolving into B cell malignancy. In the past decades, well-established clinical and serological markers have been...

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Identifiers

PMID: 26970487
DOI: 10.1016/j.autrev.2016.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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