Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inferring demography from runs of homozygosity in whole-genome sequence, with correction for sequence errors.

Molecular biology and evolution - 1 Sept 2013

MacLeod Iona M, Larkin Denis M, Lewin Harris A, Hayes Ben J, Goddard Mike E

Abstract excerpt

Whole-genome sequence is potentially the richest source of genetic data for inferring ancestral demography. However, full sequence also presents significant challenges to fully utilize such large data sets and to ensure that sequencing errors do not introduce bias into the inferred demography. Using whole-genome sequence data from two Holstein cattle, we demonstrate a new method to correct for bias caused by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Genetic Loci
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome

Share to Homozygote

Share to Linkage Disequilibrium

Share to Markov Chains

Share to Population Density

Source

Open in PubMed Open full text

Identifiers

PMID: 23842528
DOI: 10.1093/molbev/mst125
PMCID: PMC3748359

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inferring demography from runs of homozygosity in whole-genome sequence, with correction for sequence errors.PMID 23842528Read ↗

Bayesian inference of ancient human demography from individual genome sequences.Semantic proximity Read ↗

PSMC-FAC: A Statistical Framework for Correcting Loss of Heterozygosity in Low-Coverage Genomic Demographic InferenceSemantic proximity Read ↗

Mapping gene flow between ancient hominins through demography-aware inference of the ancestral recombination graphSemantic proximity Read ↗

Inferring Heterozygosity from Ancient and Low Coverage Genomes.Semantic proximity Read ↗

A Genomic Approach for Distinguishing between Recent and Ancient Admixture as Applied to Cattle.Semantic proximity Read ↗

A novel predictor of multilocus haplotype homozygosity: comparison with existing predictors.Semantic proximity Read ↗

Accurate and flexible estimation of effective population size historySemantic proximity Read ↗

Ancestral haplotype reconstruction in endogamous populations using identity-by-descent.Semantic proximity Read ↗

The effects of demography and long-term selection on the accuracy of genomic prediction with sequence data.Semantic proximity Read ↗

eSMC: a statistical model to infer admixture events from individual genomics data.Semantic proximity Read ↗

Efficient inference of population size histories and locus-specific mutation rates from large-sample genomic variation dataSemantic proximity Read ↗

Estimating divergence time and ancestral effective population size of Bornean and Sumatran orangutan subspecies using a coalescent hidden Markov model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.