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Article

Estimating divergence time and ancestral effective population size of Bornean and Sumatran orangutan subspecies using a coalescent hidden Markov model.

PLoS genetics - 1 Mar 2011

Mailund Thomas, Dutheil Julien Y, Hobolth Asger, Lunter Gerton, Schierup Mikkel H

Abstract excerpt

Due to genetic variation in the ancestor of two populations or two species, the divergence time for DNA sequences from two populations is variable along the genome. Within genomic segments all bases will share the same divergence-because they share a most recent common ancestor-when no recombination event has occurred to split them apart. The size of these segments of constant divergence depends on the...

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PMID: 21408205
DOI: 10.1371/journal.pgen.1001319
PMCID: PMC3048369

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