Article
A novel predictor of multilocus haplotype homozygosity: comparison with existing predictors.
Genetics research - 1 Dec 2009
MacLeod I M, Meuwissen T H E, Hayes B J, Goddard M E
Abstract excerpt
The patterns of linkage disequilibrium (LD) between dense polymorphic markers are shaped by the ancestral population history. It is therefore possible to use multilocus predictors of LD to infer past population history and to infer sharing of identical alleles in quantitative trait locus (QTL) studies. We develop a multilocus predictor of LD for pairs of haplotypes, which we term haplotype homozygosity (HHn): the...
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