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Article

Polymorphisms of Pyrimidine Pathway Enzymes Encoding Genes and HLA-B*40∶01 Carriage in Stavudine-Associated Lipodystrophy in HIV-Infected Patients.

PloS one - 1 Jan 2013

Domingo Pere, Mateo Maria Gracia, Pruvost Alain, Torres Ferran, Salazar Juliana, Gutierrez Maria Del Mar, Domingo Joan Carles, Fernandez Irene, Villarroya Francesc, Vidal Francesc, Baiget Montserrat, de la Calle-Martín Oscar

Abstract excerpt

PURPOSE: To assess in a cohort of Caucasian patients exposed to stavudine (d4T) the association of polymorphisms in pyrimidine pathway enzymes and HLA-B*40∶01 carriage with HIV/Highly active antiretroviral therapy (HAART)-associated lipodystrophy syndrome (HALS). METHODS: Three-hundred and thirty-six patients, 187 with HALS and 149 without HALS, and 72 uninfected subjects were recruited. The diagnosis of HALS was...

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PMID: 23840581
DOI: 10.1371/journal.pone.0067035
PMCID: PMC3694125

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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