Article
Genome-Wide Association Study of HIV-Related Lipoatrophy in Thai Patients: Association of a DLGAP1 Polymorphism with Fat Loss.
AIDS research and human retroviruses - 1 Aug 2015
Uttayamakul Sumonmal, Oudot-Mellakh Tiphaine, Nakayama Emi E, Tengtrakulcharoen Pimrapat, Guergnon Julien, Delfraissy Jean-Francois, Khusmith Srisin, Sangsajja Chariya, Likanonsakul Sirirat, Theodorou Ioannis, Shioda Tatsuo
Abstract excerpt
HIV-related lipoatrophy (LA) is a major adverse drug effect among HIV patients receiving the antiretroviral drug stavudine (d4T) in Southeast Asia. Although the development of LA could be observed in almost all HIV patients administered d4T for extended periods, there is considerable variation in the duration required to develop LA within this patient population. This study aimed to identify host genetic...
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