The cis-configuration effects of rare chromosomal fragile sites.

doi:10.1111/j.1399-0004.1990.tb03532.x

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Article

The cis-configuration effects of rare chromosomal fragile sites.

Clinical genetics - 1 Jun 1990

Côté G B

Abstract excerpt

Rare chromosomal fragile sites may adversely affect specific alleles of closely linked genes when in cis-configuration. This is illustrated by data published in Sutherland & Hecht (1985) on chromosome 16 at band q22.1.

Topics

Alleles
Chromosome Fragile Sites
Chromosome Fragility
Chromosomes, Human, Pair 16
Crossing Over, Genetic
Genetic Linkage
Humans
Phenotype

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