Pharmacogenetics in Solid Organ Transplantation: Genes Involved in Mechanism of Action and Pharmacokinetics of Immunosuppressive Drugs

Abstract excerpt

Allogenic solid organ transplantation has become the routine procedure in patients with end stage organ disease. Although the transplanted organ compensates deficient body functions, its allogenic nature requires institution of immune tolerance, nowadays provided by immunosuppressive drug administration. Both the safety and efficacy of immunosuppressive treatment depend on many factors, and maintaining levels of...

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