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Article

Genetic factors for individual administration of immunosuppressants in organ transplantation.

Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Aug 2006

Yu Song-Feng, Wu Li-Hua, Zheng Shu-Sen

Abstract excerpt

BACKGROUND: The immunosuppressive drugs used worldwide have a narrow therapeutic index, which results in a need to individualize the dose regimen for different recipients. The oxidative enzymes cytochrome P450 (CYP)3A and the drug efflux pump P-glycoprotein (P-gp) are two potential factors in the processes of metabolism. Pharmacogenetic study of immunosuppressive drugs has focused on these two enzymes. This...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16911928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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