Article
Clinical impact of polymorphisms of transport proteins and enzymes involved in the metabolism of immunosuppressive drugs.
Transplantation proceedings - 1 Jun 2009
Rosso Felipe C, de Sandes T Veras, Sampaio E L Mandia, Park S I, Silva H Tedesco, Medina Pestana J O
Abstract excerpt
Individualization of immunosuppressive therapy after solid organ transplantation is a goal that has been pursued for a long time. Nevertheless, in clinical practice, we are still stratifying patients in subgroups in which risk is assessed using demographic information and population analysis. Then, a combination of immunosuppressive drugs is chosen and doses are individualized to compensate for intra- and...
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