Article
Role of autofluorescence in flow cytometric analysis of Escherichia coli treated with bactericidal antibiotics.
Journal of bacteriology - 1 Sept 2013
Renggli Sabine, Keck Wolfgang, Jenal Urs, Ritz Daniel
Abstract excerpt
Bactericidal antibiotics kill by different mechanisms as a result of a specific interaction with their cellular targets. Over the past few years, alternative explanations for cidality have been proposed based on a postulated common pathway, depending on the intracellular production of reactive oxygen species. Detection of hydroxyl radicals relies on staining with specific fluorescent dyes that can penetrate the...
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