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Article

Asymmetrical distribution of the second messenger c-di-GMP upon bacterial cell division.

Science (New York, N.Y.) - 4 Jun 2010

Christen Matthias, Kulasekara Hemantha D, Christen Beat, Kulasekara Bridget R, Hoffman Lucas R, Miller Samuel I

Abstract excerpt

The bacterial second messenger cyclic diguanosine monophosphate (c-di-GMP) regulates cellular motility and the synthesis of organelles and molecules that promote adhesion to a variety of biological and nonbiological surfaces. These properties likely require tight spatial and temporal regulation of c-di-GMP concentration. We have developed genetically encoded fluorescence resonance energy transfer (FRET)-based...

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Identifiers

PMID: 20522779
DOI: 10.1126/science.1188658
PMCID: PMC3906730

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